3D-QSAR studies of latrunculin-based actin polymerization inhibitors using CoMFA and CoMSIA approaches
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چکیده
منابع مشابه
Design of Nonclassical DHFR Inhibitors by CoMFA and CoMSIA 3D QSAR Studies
Dihydrofolate reductase is known for important role in cancer and microbial diseases and hence is considered as validated target for aforementioned diseases. Three dimensional quantitative structure activity relationship studies (3D-QSAR) involving comparative molecular field analysis (CoMFA) and comparative similarity indices analysis (CoMSIA) were performed using twenty two Pneumocystis carin...
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ژورنال
عنوان ژورنال: European Journal of Medicinal Chemistry
سال: 2010
ISSN: 0223-5234
DOI: 10.1016/j.ejmech.2010.05.012